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Origin and Structure (GHRH Analog) Unlike AOD-9604, which isolates a small fat-metabolizing fragment of growth hormone itself, Tesamorelin is a stabilized, full-sequence analog of endogenous GHRH the upstream signal that tells the pituitary to release growth hormone in the first place

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Its clinical development for obesity was discontinued in 2007 after the pivotal 536-participant Phase IIb trial failed to meet its primary efficacy endpoint, and no formulation of the compound has received FDA approval since